![]() Haemophilia can be mild, moderate or severe, depending on the degree of the deficiency (ie how much factor is missing). Haemophilia B is caused by a deficiency in factor IX (9).Haemophilia A is caused by a deficiency in factor VIII (8).Each ‘type’ refers to the lack of a specific clotting factor. The red and dark blue females carry the gene alteration and may also have haemophilia.Īre there different types of haemophilia?.The diagrams below may assist in understanding inheritance in haemophilia. While most females who carry the gene alteration have normal clotting factor levels, around 20-30% have reduced factor levels and may have haemophilia. ![]() Sons with the gene alteration will have haemophilia.Women who carry the gene alteration causing haemophilia can pass it onto their sons and daughters.Men with haemophilia will pass the gene alteration on to their daughters but not their sons.The gene alteration causing haemophilia is passed down from parent to child through generations. However in 1/3 of cases it appears in families with no previous history of the disorder. Haemophilia is a hereditary condition and occurs in families. Read more – can females have haemophilia? How is haemophilia inherited? Some females with factor levels at the lower end of normal also experience abnormal bleeding. In very rare cases, some females have particularly low factor levels causing them to have moderate or severe haemophilia. If their factor levels fall in the range for mild haemophilia, they are now recognised as having mild haemophilia. These females used to be described as ‘symptomatic carriers’. Most females do not have symptoms of a bleeding disorder, but around 20-30% have reduced factor levels and bleeding problems. LEARN MORE – HEAR YOUNG PEOPLE’S STORIES ON THE FACTORED IN YOUTH WEBSITE Can girls have haemophilia?įemales can ‘carry’ the gene alteration responsible for haemophilia. LEARN MORE – READ PERSONAL STORIES FROM PEOPLE WITH HAEMOPHILIA Haemophilia is found in all races and all socio-economic groups. ![]() More than half have mild haemophilia and around 30% have severe haemophilia.Ĭurrent information on haemophilia statistics and treatments is available in the Australian Bleeding Disorders Registry (ABDR) Annual Report. Read the HFA Haemophilia booklet for more information about haemophilia, treatment and living well How many people have haemophilia in Australia?Ĭurrently in Australia there are more than 3,200 people diagnosed with haemophilia of varying degrees of severity. In a few very rare cases girls and women can have extremely low factor levels and have severe haemophilia. Their factor levels can be low enough to be classified as having haemophilia, usually mild haemophilia. However, around 20-30% have bleeding problems related to haemophilia. Most women and girls who carry the gene alteration do not have bleeding symptoms. Sons with the gene alteration will have haemophilia. Women who carry the gene alteration can pass it on to their sons and daughters. Men with haemophilia will pass the gene alteration on to their daughters but not their sons. The gene alteration causing haemophilia is passed down from parent to child through generations. This is called a ‘spontaneous mutation’ and occurs when there is a gene mutation or alteration during reproduction. ![]() Haemophilia is a hereditary genetic condition and occurs in families. A clotting factor is a protein in the blood that helps control bleeding. It is a blood clotting disorder where there is not enough clotting factor VIII (8) or IX (9) in the blood. Haemophilia is a lifelong condition and without proper treatment, can be life threatening.
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